Monday, July 4, 2016

On Saturday, in the quarter-final of UEFA Euro 2016, Germany defeated Italy 6–5 in a penalty shootout decider as the score was 1–1 at the end of additional time. Germany missed three penalties in the shootout, but Manuel Neuer stopped two penalties by the Italians.

Early in the first half, Bastian Schweinsteiger was substituted for German midfielder Sami Khedira following a muscle injury. The Germans had greater ball possession and also led in passing accuracy. But they had to wait till the 65th minute when Mesut Özil scored a goal. Thirteen minutes later, the lead was nullified as the Italians were awarded a penalty kick as defender Jérôme Boateng committed a handball foul in the penalty area. Stepping up for the penalty, Leonardo Bonucci scored the equaliser. This was the first goal Neuer conceded in his last 557 minutes of major tournament play. The previous record was set by Sepp Maier at 481 minutes.

The match proceeded to additional time as the score was 1–1. None of the sides could find the net in the additional time and the referee signalled a penalty shootout. Lorenzo Insigne and Toni Kroos scored their respective kicks. In the next round, Simone Zaza missed while Thomas Müller’s spot kick was saved by Gianluigi Buffon. When Andrea Barzagli scored his penalty kick and Özil missed by hitting the woodwork, Italy were 2–1 up.

Graziano Pellè missed his penalty and the Germans levelled as Julian Draxler scored. Leonardo Bonucci’s attempt to score was saved by Neuer, but Schweinsteiger wasted his chance to lead the shootout. Emanuele Giaccherini and Marco Parolo scored their spot kicks, as did Mats Hummels and Joshua Kimmich. Mattia De Sciglio’s goal was followed by Boateng’s equalising penalty. Neuer saved Matteo Darmian’s kick and Jonas Hector scored the winning penalty.

Neuer was awarded the Man of the Match award.Eighteen players stepped up for the penalty shootout equalling the record of the UEFA Euro 1980 third-place encounter. Except for these two fixtures, never has a Euro match witnessed eighteen men taking the spot kick.

Germany is to play winner of France and Iceland in the semi-final. Mats Hummels is to miss the semi-final serving a one-match ban. Striker Mario Gomez is to miss the semi-final with torn muscle fibres. Schweinsteiger pulled his knee ligaments.

Manager Joachim Löw responded to these injuries saying, “It is very bitter to lose important players in the decisive stage of the tournament. I am especially sorry for Mario. […] For us this means accepting the new situation and having to find solutions. We will do so. The quality in the squad is high and I have full confidence in all players.”

Friday, November 2, 2007

Researchers at Case Western University in Cleveland, Ohio have announced the creation of transgenic mice with substantially improved athletic endurance, which live and breed longer and are more aggressive than genetically unmodified siblings, and are leaner despite consuming 60% more food. The mice have been dubbed “mighty mice” or “supermice” by the popular press and have been compared to cyclist Lance Armstrong.

The changes were created by adding an extra copy of a single gene, PEPCK-C. This gene is already present in the mouse genome, but the modified gene is designed to be strongly active (transcribed) in skeletal muscle. (The natural copy of the gene, most active in the liver, continues to function normally). The gene mediates a crucial rate controlling step of gluconeogenesis and glyceroneogenesis, and its activity helps to allow energy production by the mitochondrial citric acid cycle. In the transgenics, more energy is available to muscle through the burning of fatty acids, with much less production of lactate (a chemical that leads to sore muscles when one exercises). This is not as major a change to the mouse genome as it might seem to the layperson. The PEPCK-C gene is already present in the mouse and a variety of natural mutations could likely cause similar results. The study appears today in the Journal of Biological Chemistry in a paper with lead author Parvin Hakimi from the laboratory of Richard W. Hanson.

The altered mice can run at 20 meters per minute (0.75 miles per hour or 1.2 kilometers per hour) for up to six kilometers (nearly four miles) without stopping. The average treadmill time for strenuous exercise on a 25-degree incline is 31.9 minutes, well in excess of the 19 minute average of unmodified mice. Females can breed at two and a half years of age, whereas most female mice cannot breed after the first year.

A colony of 500 mice has been bred, starting from six independent germline transformations (“founder” mice). The level of PEPCK-C in muscle is 9 units per gram of muscle as opposed to only 0.08 in normal mice. Levels of triglycerides and the number of mitochondria are also increased.

Hanson said that he did not expect that the results would be applicable to humans due to both practical and ethical considerations in addition to the fact that the genes might not function the same way in humans.

This is not the first time that the press has dubbed a genetically modified mouse a “mighty mouse”. Earlier scientists at John Hopkins University announced that they had made mice with massively increased muscle mass that were larger and stronger than their normal cousins. These alterations increased strength rather than endurance through the genetic modification of myostatin and follistatin, or by injection of a soluble form of ACVR2B to block myostatin activity in normal mice.

Thursday, April 9, 2009

Protests which began Monday escalated to a riot on Wednesday consisting of over 10,000 people in Chi?in?u, the capital of Moldova, protesting the results of Sunday’s 2009 Moldovan parliamentary election, which showed an apparent, narrow victory for the Communist Party (Partidul Comuni?tilor din Republica Moldova, PCRM). Demonstrators claim the victory was the result of electoral fraud.

The demonstration escalated to a “flash mob” of between 10,000 to 15,000 communicating via online tools like email, micro-blogging tool Twitter, and social-networking website Facebook. “We sent messages on Twitter but didn’t expect 15,000 people to join in. At the most we expected 1,000”, said Oleg Brega of the activist group Hyde Park.

Police deployed tear gas and water cannons, and fired blanks into the crowd. The rioters threw stones at the riot police and took control of the parliament building and presidential office. A bonfire was built out of parliamentary furniture and all windows below the 7th floor were broken.

Approximately one hundred protesters and 170 police officers are reported as injured. There have been conflicting reports as to whether a female protester died during the altercation.

193 protesters “have been charged with looting, hooliganism, robbery and assault,” said an Interior Ministry spokesperson. This announcement sparked another protest by those demanding the release for those detained.

There is wide speculation about who was to blame for the rioting.

President Vladimir Voronin has expelled the Romanian ambassador from Moldova, blaming Romania for the violent protests. “We know that certain political forces in Romania are behind this unrest. The Romanian flags fixed on the government buildings in Chisinau attest to this” said Voronin. “Romania is involved in everything that has happened.“ Voronin also blamed the protests on opposition leaders who used violence to seize power, and has described the event as a coup d’état.

Protesters initially insisted on a recount of the election results and are now calling for a new vote, which has been rejected by the government. Rioters were also demanding unification between Moldova and Romania. “In the air, there was a strong expectation of change, but that did not happen”, said OSCE spokesman Matti Sidoroff.File:Dorin Chirtoaca.jpg

“The elections were fraudulent, there was multiple voting” accused Chi?in?u mayor Dorin Chirtoac? of the Liberal Party. “It’s impossible that every second person in Moldova voted for the Communists. However, we believe the riots were a provocation and we are now trying to reconcile the crowd. Leaders of all opposition parties are at the scene,” said Larissa Manole of the Liberal Democratic Party of Moldova.

The Organisation for Security and Cooperation in Europe (OSCE) proclaimed the PCRM to have won 61 seats in initial counts, enough to guarantee a third term in power for Voronin, who has held the position since 2001. But the Central Election Commission has received evidence of election violations, according to RIA Novosti, and upon recounts conducted of disputed polls, the commission reported that the Communists achieved 49.48% of the Moldovian vote, giving them 60 parliamentary seats — one short of the total needed to win the presidential election. “The electoral commission also granted opposition parties permission to check voter lists, fulfilling one of their chief demands,” said Yuri Ciocan, Central Election Commission secretary.

Voronin will step down in May, however his party could elect a successor with 61 parliamentary seats without any votes from outside parties as well as amend the Constitution. With the PCRM garnering 60 seats, the opposition will have a voice in the presidential election for a new successor.

The western part of Moldova was a part of Romania from the Romania’s independence until the region was detached by the USSR in 1940 to form the Moldavian Soviet Socialist Republic. On independence in 1990 the country sought union with Romania but the eastern, Russian- and Ukrainian-inhabited areas of the country declared themselves independent from Moldova and formed the state of Transnistria and movement toward union was halted.

Moldova is Europe’s poorest country, where average income is less than $250 (£168) a month. The country’s neighbours are Romania and Ukraine. Romania is a European Union (EU) state.

Friday, May 26, 2006

In February of 2006, the Savarino Services Construction Corp. proposed the construction of a seven million dollar hotel on Elmwood and Forest Avenues in Buffalo, New York. In order for the hotel to be built, at least five properties containing businesses and residents would have to be destroyed. It was not certain whether the properties were owned by Savarino or by the landlord Hans Mobius. The hotel was designed by Karl Frizlen of the Frizlen Group, and is planned to be a franchise of the Wyndham Hotels group.

Elmwood Avenue is known by the community as a popular shopping center, and Nancy Pollina of Don Apparel (who is “utterly against” the construction) claims it’s the only reason why students from Buffalo State College leave campus. Additionally, Michael Faust of Mondo Video said he did not want to “get kicked out of here [his video store property].”

In 1995, a Walgreens was proposed to be built on the same land, but Walgreens later withdrew its request for a variance because of pressure from the community. More recently, Pano Georgiadis tried to get the rights to demolish the Atwater House next to his restaurant on Elmwood Avenue, but was denied a permit due to the property’s historical value. He has since been an opponent to the hotel construction.

In the process of debating the hotel, it was thought that a hotel had previously existed on the proposed site, however; research done at the Buffalo and Erie County Historical Society had shown that no hotel had previously existed on the site.

Friday, November 2, 2007

Researchers at Case Western University in Cleveland, Ohio have announced the creation of transgenic mice with substantially improved athletic endurance, which live and breed longer and are more aggressive than genetically unmodified siblings, and are leaner despite consuming 60% more food. The mice have been dubbed “mighty mice” or “supermice” by the popular press and have been compared to cyclist Lance Armstrong.

The changes were created by adding an extra copy of a single gene, PEPCK-C. This gene is already present in the mouse genome, but the modified gene is designed to be strongly active (transcribed) in skeletal muscle. (The natural copy of the gene, most active in the liver, continues to function normally). The gene mediates a crucial rate controlling step of gluconeogenesis and glyceroneogenesis, and its activity helps to allow energy production by the mitochondrial citric acid cycle. In the transgenics, more energy is available to muscle through the burning of fatty acids, with much less production of lactate (a chemical that leads to sore muscles when one exercises). This is not as major a change to the mouse genome as it might seem to the layperson. The PEPCK-C gene is already present in the mouse and a variety of natural mutations could likely cause similar results. The study appears today in the Journal of Biological Chemistry in a paper with lead author Parvin Hakimi from the laboratory of Richard W. Hanson.

The altered mice can run at 20 meters per minute (0.75 miles per hour or 1.2 kilometers per hour) for up to six kilometers (nearly four miles) without stopping. The average treadmill time for strenuous exercise on a 25-degree incline is 31.9 minutes, well in excess of the 19 minute average of unmodified mice. Females can breed at two and a half years of age, whereas most female mice cannot breed after the first year.

A colony of 500 mice has been bred, starting from six independent germline transformations (“founder” mice). The level of PEPCK-C in muscle is 9 units per gram of muscle as opposed to only 0.08 in normal mice. Levels of triglycerides and the number of mitochondria are also increased.

Hanson said that he did not expect that the results would be applicable to humans due to both practical and ethical considerations in addition to the fact that the genes might not function the same way in humans.

This is not the first time that the press has dubbed a genetically modified mouse a “mighty mouse”. Earlier scientists at John Hopkins University announced that they had made mice with massively increased muscle mass that were larger and stronger than their normal cousins. These alterations increased strength rather than endurance through the genetic modification of myostatin and follistatin, or by injection of a soluble form of ACVR2B to block myostatin activity in normal mice.

Wednesday, July 21, 2010

A televised debate between Australia’s candidates for Prime Minister in the upcoming election has been rescheduled and shortened — to avoid a clash with popular cookery show MasterChef.

The pre-election debate traditionally lasts 90 minutes and occurs at 1930 on the first Sunday of the campaign.

With the grand finale of the cooking competition already scheduled for that time, and expected to attract around four million viewers, the decision has been made to move the debate forward to 1830 and shorten it to 60 minutes.

When asked about MasterChef, Prime Minister Julia Gillard replied: “I can understand the fascination with cooking and eating, so I know many Australians will watch that show. But I think Australians still pay some regard to the debate and the election campaign.”

The debate between Gillard and her Liberal/National Coalition primary opponent Tony Abbott has already been the subject of controversy. Former PM Kevin Rudd had committed to holding three debates before the election. Gillard insisted she only wanted one.

Australian Greens leader Bob Brown had also wished to be part of the debate, but joked that he probably had more chance of appearing on MasterChef.

Friday, November 13, 2009

Italian goalkeeper Carlo Cudicini has been seriously injured in a motorcycle accident in London. The player, who plays for Tottenham Hotspurs, was involved in a collision with a car at 10:30 GMT. The football club reported that he has fractured his wrists and injured his pelvis.

A spokesperson for the Metropolitan Police released a statement saying “A 36-year-old male suffered injuries described by the London Ambulance Service as possibly life-changing and was taken to Whipps Cross Hospital for further assessment and treatment”. No arrests have been made.

Cudicini crashed his motorcycle into a Ford Fiesta with a female driver and a child passenger. Neither the driver or passenger were injured in the accident.

Cudicini is the son of former AC Milan goalkeeper Fabio Cudicini. During his career he has played for Lazio, AC Milan and Chelsea. He played for Chelsea for 10 years until he was transferred to Tottenham in January. He made one appearance for the Italian national team.

Sunday, November 23, 2008

A Pembroke Pines, Florida teenager killed himself Wednesday, November 19, while broadcasting on the live video site Justin.tv. After making suicide threats and being encouraged by Justin.tv viewers and Bodybuilding.com forum members, Abraham K. Biggs, 19, committed suicide by taking an overdose of opiates and benzodiazepine, which had been prescribed for his bipolar disorder.

Biggs first began blogging about his planned suicide 12 hours before the actual event. He died after taking pills and lying on the bed in front of the webcam. After the broadcast, viewers who apparently thought it was a hoax posted messages such as “OMG”, “LOL”, and “hahahah”.

Hours later, after being alerted by viewers who had noticed that Biggs had stopped breathing, law enforcement and paramedics arrived, discovered his body, and covered the camera. The Broward County Medical Examiner’s Office has reportedly confirmed Biggs’ death.

According to Montana Miller of the Bowling Green State University, the circumstances of this case were not shocking: “If it’s not recorded or documented, then it doesn’t even seem worthwhile. For today’s generation it might seem, ‘What’s the point of doing it if everyone isn’t going to see it?'”

Biggs’ sister Rosalind was angry that neither the website nor its viewers reacted soon enough to save him. “They got hits, they got viewers, nothing happened for hours,” she said. She described him as “very happy” and “friendly and outgoing.” “On a normal day, you couldn’t really tell that he got as low as he did.” However, he did have relationship problems with his girlfriend, according to a friend.

Mental health professionals have warned about the possibility that other mentally troubled people would copy his actions. According to Dr. David Shaffer of Columbia University, “Any video showing it as heroic or romantic or glamorous could reduce the anxiety people might feel about suicide. It becomes a respectable behavior and lowers the threshold of suicide.” He and other psychiatrists recommend that potentially suicidal teens talk to others and “tell what’s going on.”

Monday, September 7, 2015

The US economy added 173,000 jobs in August, the Bureau of Labor Statistics reported on Friday. The unemployment rate fell from 5.3 to 5.1 percent, the lowest since April 2008.

Although August job gains were lower than most economists forecast, job growth numbers for June and July were revised upwards by a combined 44,000. Average job gains over the past three months stand at 221,000, compared to March-May’s 189,000 monthly average. Over the past twelve months, job growth has averaged 247,000 per month.

Average hourly earnings rose 0.3 percent, or 8 cents, marking the largest increase in earnings in seven months. Hourly earnings had risen by 6 cents in July. Wages have risen by 2.2 percent over the past year.

Job growth in August was primarily concentrated in the health care and social assistance, financial activities, and professional and business services sectors. Those three areas of the economy added a combined 108,000 jobs. Food service and drinking places employment increased by 26,000 over the month, and other economic sectors saw employment hold steady. Manufacturing, on the other hand, saw employment decline by 17,000 in August. A stronger dollar and worldwide economic weakness make US exports less desirable, leading to a flattening in manufacturing employment so far this year after steadily rising in the early years of the US economic recovery.

The solid overall job gains led analysts to slightly raise expectations for a decision by the Federal Reserve to raise interest rates this month. Investors raised the likelihood of a September rate increase from 26 percent before the jobs report to 30 percent, and stocks dropped by over one percent on Friday. “The payrolls data is certainly good enough to allow for a Fed rate hike in September,” said Deutsche Bank’s head of currency strategy, Alan Ruskin. “The big question is still whether financial market volatility will scupper the plans.”

“This is the first time the market has looked at a Fed meeting and really has no idea what the Fed is going to do,” said Mark Kepner, a New Jersey equity trader with Themis Trading. “Right now you’re looking at the overall uncertainty and that’s what’s hanging on the market. I don’t think this number in and of itself changes how somebody’s going to vote.”